摘要 : Zeolitic imidazole framework-67 (ZIF-67) was demonstrated to exhibit intrinsic peroxidase-like activity by using 3,3',5,5'-tetramethylbenzidine (TMB) as a chromogenic substrate. However, due to the inherent defects in the chemical... 展开 Zeolitic imidazole framework-67 (ZIF-67) was demonstrated to exhibit intrinsic peroxidase-like activity by using 3,3',5,5'-tetramethylbenzidine (TMB) as a chromogenic substrate. However, due to the inherent defects in the chemical stability and thermal stability of ZIFs, the peroxidase-like activity of ZIF-67 was severely affected. Therefore, establishing a simple and effective method to enhance the stability of ZIF-67 is necessary. ATP was found to improve die catalytic activity of ZIF-67. On the one hand, compared with ZIF-67, the catalytic efficiency of ZIF-67/ATP increased by 796 %, 5010 % and 570 % at 25 0C, 30 0C and 40 0C, respectively. In addition, die catalytic activity of ZIF-67/ATP was also greatly enhanced at pH-4. On the otiier hand, compared witii ATP, die catalytic rate of ZIF-67/ATP increased by 364 % after 10 min of incubation. Inspired by die high catalytic activity of ZIF-67/ATP, we used the ZIF-67/ATP peroxidase-like system for colorimetrie detection of glutathione with the limit of detection (LOD) of 0.46 uM. Furthermore, the proposed method provides a perspective on stabilizing the structures of ZIFs and developing a simple and efficient detection method. 收起