摘要 : The reduction of acetophenone with borane-THF over heterogeneous catalysts prepared by reacting nickel-boride with (1R, 2S)-(-)-norephedrine, afforded (R)-(+)-1-phenylethanol with high enantioselectivity (ee = 90%). The catalysts ... 展开 The reduction of acetophenone with borane-THF over heterogeneous catalysts prepared by reacting nickel-boride with (1R, 2S)-(-)-norephedrine, afforded (R)-(+)-1-phenylethanol with high enantioselectivity (ee = 90%). The catalysts can be recycled two times with little or no loss of performance. The excellent enantioselective properties resulted from the formation of 1, 3, 2-oxazaborolidine which is strongly anchored at the surface of the nickel-boride. Used for the hydrogenation of acetophenone, 4-methylpentan-2-one and isophorone, the catalyst hydrogenated with a slight predominance of the S configuration. The ee was poor but it remained constant when the catalyst was reused. 收起