摘要 : This study details the first diagnosis of <i>Francisella</i> sp. in tilapia in the United Kingdom. Losses of tilapia fry at a recirculation fish farm in England were investigated, giving a presumptive positive diagnosis of infecti... 展开 This study details the first diagnosis of <i>Francisella</i> sp. in tilapia in the United Kingdom. Losses of tilapia fry at a recirculation fish farm in England were investigated, giving a presumptive positive diagnosis of infection with <i>Francisella</i> sp. by histopathological examination. Most fish sampled showed moderate to marked pathology of the major organs, with lesions being present in most tissues. The most obvious host response was granuloma formulation. A subsequent follow-up visit provided further evidence for the presence of a <i>Francisella</i> species. PCR amplicons were obtained using <i>Francisella</i> spp.-specific primers that shared 100% sequence identity with the 16S rRNA gene of the type strain of the species <i>F. asiatica</i> previously described as the cause of disease in tilapia in Southeast Asia and Central America. This outbreak and the subsequent investigation emphasise the importance of strict biosecurity at fish farms and the care that needs to be taken when using a new supplier of fish. 收起