摘要 : Purpose The formation of retinal neovascularization (RNV) is the primary pathological process underlying retinopathy of prematurity (ROP). Previous studies have shown that inflammatory factors are related to the formation of RNV. ... 展开 Purpose The formation of retinal neovascularization (RNV) is the primary pathological process underlying retinopathy of prematurity (ROP). Previous studies have shown that inflammatory factors are related to the formation of RNV. Tumor necrosis factor-alpha (TNF-alpha), as an important factor in the inflammatory response, is involved in the regulation of RNV formation. However, the mechanism through which TNF-alpha inhibition reduces RNV formation is not fully clarified. Therefore, the purpose of this study was to explore the effect of etanercept, an inhibitor of TNF-alpha, on RNV, and its possible mechanism. 收起