摘要 : Background: Electrochemical advanced oxidation processes (EAOPs) have received considerable attention due to their ability to transform or mineralize emerging organic contaminants. Methods: Herein, we report that MnO2 covered with... 展开 Background: Electrochemical advanced oxidation processes (EAOPs) have received considerable attention due to their ability to transform or mineralize emerging organic contaminants. Methods: Herein, we report that MnO2 covered with polyelectrolyte films has been fabricated using layer-bylayer (LBL) assembly to modify the anode for efficient oxytetracycline (OTC) oxidation in water. Significant Findings: It is found that over 89.19% of OTC was degraded in 20 min in this EAOPs system with MnO2@(PSS/PDDA)2PSS modified anode. Quenching experiments and electron-spin resonance (ESR) spectra have shown that hydroxyl radicals ('OH) and direct electron transfer play the dominant roles in OTC oxidation. Several possible pathways of OTC degradation were proposed on the basis of the by-products detected by liquid chromatography-mass spectrometry (LC-MS). Toxicity Estimation Software Tool (T.E.S.T) based on quantitative structure-activity relationships (QSARs) revealed increased toxicity of several transformation products. Moreover, flow cytometry method was applied to quantify the cytotoxic effects of the reaction solution. It may provide an alternative approach to design metal oxide/polymer composites modified anodes for contaminants degradation. It is notable that toxicological assessment of the transformation products is essential especially for newly developed anode materials. (c) 2022 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved. 收起