摘要 : Breast cancer is considered the most prevalent disease among women worldwide. It is ranked second in the world in terms of mortality rate of women due to cancer, with lung cancer still being the first. The treatment option breast ... 展开 Breast cancer is considered the most prevalent disease among women worldwide. It is ranked second in the world in terms of mortality rate of women due to cancer, with lung cancer still being the first. The treatment option breast cancer becomes limited and stands therapeutically substantial due to its associated systemic toxicities. In spite the various advanced in treatment modalities, there is no reduction in the rate of mortality. Recent studies have shown more focus of the researchers towards the herbal medicines, their method of formulation and their usefulness in the prevention and treatment of breast cancer. It is observed that the herbal bioactives have less bioavailability and less therapeutic efficacy owing to their hydrophobic nature. This in turn led to the advancement in the formulation technologies like slight modification for the herbal nano-formulation to form targeted drug delivery system. These systems could have the potential to reduce the associated toxicities related to the anti-cancer drugs and conventional drugs with increase in the bioavailability and therapeutic efficacy. This review discusses the studies which focus on different nano carriers loaded with herbal molecules for the treatment of breast cancer with/without synthetic drug, systematically using PRISMA guidelines. These different nano-formulations can give the reader broad information on the delivery aspect and the techniques used for the preparation of the herbal nano-formulation and their in vivo study. 收起