摘要 : Four novel lignans, aglacins E-H (1-4), were isolated and identified from the methanolic extract of the stem bark of Agalia cordata collected in Indonesia. All of these metabolites contain two unusual contiguous trimethoxylated ph... 展开 Four novel lignans, aglacins E-H (1-4), were isolated and identified from the methanolic extract of the stem bark of Agalia cordata collected in Indonesia. All of these metabolites contain two unusual contiguous trimethoxylated phenyl systems. While two of these compounds (1 and 2) are aryltetralin cyclic ether lignans, a third lignan (3) exhibits an unusual formyl group whereas compound (4) is a rare norlignan. The structures of all compounds were elucidated by interpretation of 1D and 2D NMR, as well as by low- and high-resolution EIMS. The absolute configurations of agalcins E and F (1 and 2) were determined by the modified Mosher's method. 收起