摘要
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<ce:abstract xmlns:ce="http://www.elsevier.com/xml/common/dtd" xmlns="http://www.elsevier.com/xml/ja/dtd" class="author-highlights" xml:lang="en" id="ab005" view="all"><ce:section-title id="st005">Highlights</ce:section-title><ce:...
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<ce:abstract xmlns:ce="http://www.elsevier.com/xml/common/dtd" xmlns="http://www.elsevier.com/xml/ja/dtd" class="author-highlights" xml:lang="en" id="ab005" view="all"><ce:section-title id="st005">Highlights</ce:section-title><ce:abstract-sec id="as005" view="all"><ce:simple-para id="sp0005" view="all"><ce:list id="l0005"><ce:list-item id="o0005"><ce:label>•</ce:label><ce:para id="p0005" view="all"><ce:italic>Rosa dumalis</ce:italic>,<ce:italic>R. dumetorum</ce:italic>and<ce:italic>R. sempervirens</ce:italic>hips were subject of this study.</ce:para></ce:list-item><ce:list-item id="o0010"><ce:label>•</ce:label><ce:para id="p0010" view="all">Study included fresh and air-dried rose hips, purée and jam of each species.</ce:para></ce:list-item><ce:list-item id="o0015"><ce:label>•</ce:label><ce:para id="p0015" view="all">Phenolic profile and ascorbic acid content were investigated.</ce:para></ce:list-item><ce:list-item id="o0020"><ce:label>•</ce:label><ce:para id="p0020" view="all">Antioxidant activity was determined using six<ce:italic>in vitro</ce:italic>assays.</ce:para></ce:list-item><ce:list-item id="o0025"><ce:label>•</ce:label><ce:para id="p0025" view="all">Anti-acetylcholinesterase, anti-inflammatory and cytotoxic activities were examined.</ce:para></ce:list-item></ce:list></ce:simple-para></ce:abstract-sec></ce:abstract><ce:abstract xmlns:ce="http://www.elsevier.com/xml/common/dtd" xmlns="http://www.elsevier.com/xml/ja/dtd" class="author" xml:lang="en" id="ab010" view="all"><ce:section-title id="st010">Abstract</ce:section-title><ce:abstract-sec id="as010" view="all"><ce:simple-para id="sp0010" view="all">The aim of the present study was investigation of the phenolic profile, ascorbic acid content, antioxidant, anti-acetylcholinesterase, anti-inflammatory and cytotoxic activity of rose hips and the preserves (purée and jam) of three insufficiently examined<ce:italic>Rosa</ce:italic>species:<ce:italic>Rosa dumalis</ce:italic>Bechst.,<ce:italic>R. dumetorum</ce:italic>Thuill. and<ce:italic>R. sempervirens</ce:italic>L. The liquid chromatography–tandem mass spectrometry analysis resulted in quantification of 14 of the 45 phenolic compounds examined, with ellagic acid as the most dominant. Notable antioxidant activity of all three species was confirmed through several assays. Moderate inhibition of acetylcholinesterase by extracts of all investigated<ce:italic>Rosa</ce:italic>species was observed. Several extracts of examined<ce:italic>Rosa</ce:italic>species demonstrated inhibition potency towards production of some monitored eicosanoids in cyclooxygenase-1 and 12-lipoxygenase pathways. Two<ce:italic>R. sempervirens</ce:italic>extracts exerted cytotoxic activity against HeLa and HT-29 cell lines, but were inactive towards MRC-5 and MCF7. The results support the potential of these rose hips as food with health-promoting properties.</ce:simple-para></ce:abstract-sec></ce:abstract>
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