摘要 : AIM To evaluate the impact of the timing of capsule endoscopy(CE)in overt-obscure gastrointestinal bleeding(OGIB).METHODS Retrospective,single-center study,including patients submitted to CE in the setting of overt-OGIB between Ja... 展开 AIM To evaluate the impact of the timing of capsule endoscopy(CE)in overt-obscure gastrointestinal bleeding(OGIB).METHODS Retrospective,single-center study,including patients submitted to CE in the setting of overt-OGIB between January 2005 and August 2017.Patients were divided into 3 groups according to the timing of CE(≤48 h;48 h-14 d;≥14 d).The diagnostic and therapeutic yield(DY and TY),the rebleeding rate and the time to rebleed were calculated and compared between groups.The outcomes of patients in whom CE was performed before(≤48 h)and after 48 h(>48 h),and before(<14 d)and after 14 d(≥14 d),were also RESULTS One hundred and fifteen patients underwent CE for overt-OGIB.The DY was 80%,TY-46.1%and rebleeding rate-32.2%.At 1 year 17.8%of the patients had rebled.33.9%of the patients performed CE in the first 48 h,30.4%between 48h-14d and 35.7%after 14 d.The DY was similar between the 3 groups(P=0.37).In the≤48 h group,the TY was the highest(66.7%vs 40%vs 31.7%,P=0.005)and the rebleeding rate was the lowest(15.4%vs 34.3%vs 46.3%P=0.007).The time to rebleed was longer in the≤48 h group when compared to the>48 h groups(P=0.03).CONCLUSION Performing CE within 48 h from overt-OGIB is associated to a higher TY and a lower rebleeding rate and longer time to rebleed. 收起