摘要 : A catalytic, enantioselective Michael addition of beta-keto esters to alpha,beta-unsaturated carbonyl compounds was achieved by using a chiral biquinoline N,N'-dioxide-scandium trifluoromethanesulfonate complex as a catalyst. The ... 展开 A catalytic, enantioselective Michael addition of beta-keto esters to alpha,beta-unsaturated carbonyl compounds was achieved by using a chiral biquinoline N,N'-dioxide-scandium trifluoromethanesulfonate complex as a catalyst. The corresponding Michael adducts were obtained in high yields and with enantioselectivities up to 84% ee. (C) 2003 Elsevier Ltd. All rights reserved. [References: 58] 收起