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In this chapter, the authors review the history of the Waterloo Longitudinal Proj-ect (WLP), the first longitudinal study (1980-1992) dedicated to the study ofsocial withdrawal, its correlates, and consequences. Theories underlyin...
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In this chapter, the authors review the history of the Waterloo Longitudinal Proj-ect (WLP), the first longitudinal study (1980-1992) dedicated to the study ofsocial withdrawal, its correlates, and consequences. Theories underlying theWLP are described, as are its empirical findings. Recent research from other labsthat has extended the findings of the original WLP is briefly described. Theauthors' research that draws on the findings of WLP are noted as well. An under-lying theme in this work is that relationships (and interactions) with parentsand friends can serve as protective or exacerbating factors in the developmentalcourse of social withdrawal and its concomitants (including social anxiety).
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Introduction. We performed a retrospective study to evaluate demographics, clinical course, outcome, and radiological findings of children with respiratory syncytial virus (RSV) infection. Methods. Four hundred patients admitted b...
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Introduction. We performed a retrospective study to evaluate demographics, clinical course, outcome, and radiological findings of children with respiratory syncytial virus (RSV) infection. Methods. Four hundred patients admitted between October 2013 and May 2016 were enrolled. Clinical and radiographic trends were evaluated for association with severity of RSV presentation. Severity was defined as hospitalization >2 days, pediatric intensive care unit admission, or need for mechanical ventilation. Results. Common clinical findings included fever (78.5%), coughing (97%), rhinorrhea/congestion (93%), and hypoxia (44.8%). Hypoxia was seen in 64.7% of the severe group compared with 32.0% in the nonsevere group (P < .001). Airspace opacification was seen in 49.2% of chest X-rays of the severe group compared with 26.4% in the nonsevere group (P < .001). Conclusion. Higher incidence of hypoxia or airspace opacification on chest X-ray may be predictors of poorer outcomes for patients with RSV infection.
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Purpose: To investigate the presence of relevant vascular and incidental extravascular findings in patients undergoing magnetic resonance angiography (MRA) of the thoracic aorta and origin of the great vessels.
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Background: In recent years, the number of liver transplantations for advanced-stage liver diseases has considerably increased and the patients have a wide range of der-matologic manifestations. Aim: This study aims to reveal cuta...
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Background: In recent years, the number of liver transplantations for advanced-stage liver diseases has considerably increased and the patients have a wide range of der-matologic manifestations. Aim: This study aims to reveal cutaneous, mucosal, and nail lesions in liver transplant recipients in quite large patient series. Patients/Methods: The study included 520 patients in the Inonu University Liver Transplantation Institute. New and followed-up patients attended to the study between May and October 2019. The patients were examined by a dermatologist, and their data were recorded. Results: The study included 163 female and 357 male patients with the main age of 44.20 ± 18.18 (range: 1-83 years), and 465 livers (89.4%) were taken from live donors, while 54 livers (10.4%) were taken from cadavers. A total of 314 (60.4%) patients had dermatophyte infections, 174 (33.4%) patients had pathological nail changes, and 427 (82.1%) patients had oral mucosal lesions. Graft-versus-host disease (GVHD) developed in 9 (1.73%) patients after the transplantation, and 5 patients died of GVHD. Four patients had cutaneous malignancies. Conclusions: Tumoral and nontumoral dermatological diseases may be encountered following the transplantation depending on underlying liver disease, immunosup-pressive treatment, the graft itself, or any primary cutaneous disease. Liver transplantation recipients require a multidisciplinary clinical approach, and dermatological care must be an integral part of this approach.
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Purpose: There is debate within the genetics community about the optimal term to describe genetic variants unrelated to the test indication but potentially important for health. Given the lack of consensus and the importance of ad...
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Purpose: There is debate within the genetics community about the optimal term to describe genetic variants unrelated to the test indication but potentially important for health. Given the lack of consensus and the importance of adopting terminology that promotes effective clinical communication, we sought the opinion of clinical genetics patients.
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The study was conducted on the clinical cases of neuromuscular disorders in hind quarter in dogs reported at IVRI Polyclinic, Izatnagar (U.P.). The cases of hind quarter weakness were selected from the cases of neuromuscular disor...
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The study was conducted on the clinical cases of neuromuscular disorders in hind quarter in dogs reported at IVRI Polyclinic, Izatnagar (U.P.). The cases of hind quarter weakness were selected from the cases of neuromuscular disorders and classified in to groups I(Animals with hindquarter weakness, which could stand, and had staggering gait and intact pain sensation), II (Animals with hind quarter paresis, which were unable to stand and dragged hind legs while walking with intact pain sensation) andIII (Hind quarter paralysis with absence of pain sensation) on the basis of history, clinical signs, radiographic and neurological examination.Various radiographic features were also recorded.
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Acute intoxication caused by consumption of oak (Quercus infectoria subsp. boissieri) occurred in a flock of 92 lambs in Elazig, a province of the eastern Turkey. Four lambs had died with a history of anorexia and recumbency follo...
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Acute intoxication caused by consumption of oak (Quercus infectoria subsp. boissieri) occurred in a flock of 92 lambs in Elazig, a province of the eastern Turkey. Four lambs had died with a history of anorexia and recumbency following introduction approximately 150 g per animal/day oak material for 10-13 days. Clinical, pathological and biochemical findings were documented in 3 lambs. The most striking biochemical changes were detected in blood urea nitrogen levels and gamma-glutamyl transferase activity. At necropsy; subcutaneous edema, mild hydrothorax, moderate ascites, severe perirenal and retroperitoneal edema, severe multifocal renal subcapsular petechiation were the major gross findings detected in all cases. Renal histopathology revealed moderate multifocal tubular cell necrosis, multifocal moderate cell swelling, multifocal tubular dilatation and hyaline cast formations. The results of this study suggest that both plant and animal based factors; namely the young age and high tannin content might contribute to the occurrence of the present toxicosis in the lambs.
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Objective. - To study the frequency and management of incidental findings in nonenhanced brain MRI of a middle-aged population of type 2 diabetic patients.
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IntroductionThe significance of MRI findings of patients with Parinaud syndrome (PS) with respect to clinical characteristics is poorly defined. Over the past decades, all patients with PS undergo magnetic resonance imaging which ...
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IntroductionThe significance of MRI findings of patients with Parinaud syndrome (PS) with respect to clinical characteristics is poorly defined. Over the past decades, all patients with PS undergo magnetic resonance imaging which allows a better identification of the lesion localization. We compared the neuro-ophthalmological findings of patients with PS caused by intrinsic (intra-axial) vs extrinsic (pineal gland tumor) brainstem lesions.
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Introduction: Ocular problems as refractive errors, strabismus, accommodation, and cataract are well known in children with Down syndrome (DS). However, there is little information on the possible correlation of eye problems with ...
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Introduction: Ocular problems as refractive errors, strabismus, accommodation, and cataract are well known in children with Down syndrome (DS). However, there is little information on the possible correlation of eye problems with systemic diseases such as heart defect (with or without surgery), hypotony, hypothyroidism, hearing loss, and others. Methods: Ophthalmic problems versus certain systemic diseases were studied in 65 children with DS, aged 2 months to 13 years, referred to the University Eye Hospital Ljubljana, Slovenia from 2008 to 2010. Standard ophthalmic examination methods were used, and physical data were taken from pediatric records. Results: Ocular findings included nystagmus (29.2%), esotropia (26.1%), epiphora (21.5%), Brushfield spots (16.9%), lens opacities (12.3%), abnormalities of the retinal vessels, foveal hypoplasia, or retinal pigment epithelium hyperplasia (32.2%), and optic disc pallor (7.6%). Hyperopia (36.9%) was the most frequent refractive error in the group, followed by astigmatism (29.2%) and myopia (24.6%). No diagnosed systemic abnormalities were found in 18.3% of the children, while 30.7% had congenital heart defect. Hypothyroidism, hypotony, hearing loss, gastrointestinal tract malformations, and leukemia were less common. Nystagmus was related to myopia and esotropia, and to heart disease and heart operations. Conclusions: Comorbidities are common in DS and complicate diagnosis, development, and therapy.
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