摘要 : Histopathological examination of the central nervous system is essential for the confirmation of a TSE diagnosis. Typical lesions are spongiform changes of the grey matter. intraneuronal vacuoles in particular nuclei of the brain ... 展开 Histopathological examination of the central nervous system is essential for the confirmation of a TSE diagnosis. Typical lesions are spongiform changes of the grey matter. intraneuronal vacuoles in particular nuclei of the brain stein, gliosis and neuronal degeneration. The nature of the lesions is similar between species. However, the variation in the distribution and severity of the changes is striking. 收起