摘要 : Reaction of delta-(sulfonyl)amino-alpha-epoxy ketones with dimethylhydrazine results in cyclization to pyrrolidine-fused beta-hydroxy dimethylhydrazones. elimination affords dihydropyrroles which can be converted to sulfonyl-prote... 展开 Reaction of delta-(sulfonyl)amino-alpha-epoxy ketones with dimethylhydrazine results in cyclization to pyrrolidine-fused beta-hydroxy dimethylhydrazones. elimination affords dihydropyrroles which can be converted to sulfonyl-protected ketopyrroles via oxidation with NIS; alternatively, treatment with DBU affords N-H bearing ketopyrroles. Copyright (C) 1996 Elsevier Science Ltd [References: 21] 收起