摘要 : In this chapter, we first briefly review the history of Zika virus (ZIKV) over the past 70 years since its discovery. We then focus on the ZIKV NS2B/NS3 protease, a major potential target for anti-ZIKV therapeutics. We describe th... 展开
作者 | Hilgenfeld~ Rolf Lei~ Jian Zhang~ Linlin |
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作者单位 | |
期刊名称 | 《Advances in Experimental Medicine and Biology》 |
总页数 | 15 |
语种/中图分类号 | 英语 / R3 |
关键词 | Zika virus history Zika virus disease congenital Zika syndrome Zika virus protease boronic-acid inhibitor Zika virus protease dimerization X-ray crystallography NMR spectroscopy anti-Zika virus drug discovery |
馆藏号 | N2007EPST0000298 |