摘要 : An improved carboxylation method of (OC-6-33)-dichloro-(ethane- 1,2-diamine)dihydroxyplatinum(IV) based on succinic anhydride is reported. Reaction of the uncoordinated carboxylic acid with simple amines and alcohols leads to the ... 展开 An improved carboxylation method of (OC-6-33)-dichloro-(ethane- 1,2-diamine)dihydroxyplatinum(IV) based on succinic anhydride is reported. Reaction of the uncoordinated carboxylic acid with simple amines and alcohols leads to the corresponding amides and esters in the presence of 1,1'-carbonyldiimidazole. The resulting new complexes are characterized by IR, H-1, C-13, N-15, and Pt-195 NMR spectroscopy, mass spectrometry, and elemental analysis. This reaction provides an entry to a new class of kinetically inert platinum(IV) complexes. 收起