摘要 : Rapid and simple synthesis of oligosaccharides related to one of the terminal motifs of mycobacterial lipoarabinomannan is described. An array of homologous linear alpha(1 -> 5)-linked oligoarabinofuranosides with 4-(2-chloroethox... 展开 Rapid and simple synthesis of oligosaccharides related to one of the terminal motifs of mycobacterial lipoarabinomannan is described. An array of homologous linear alpha(1 -> 5)-linked oligoarabinofuranosides with 4-(2-chloroethoxy)phenyl aglycon and selectively unprotected 5-OH group at the non-reducing end was obtained by oligomerization of 3-O-benzoyl beta-D-arabinofuranose 1,2,5-orthobenzoate. Subsequent introduction of beta(1 -> 2)-linked arabinofuranose disaccharide moiety by step-wise glycosylation furnished the target oligosaccharides which were conjugated with bovine serum albumin. (C) 2016 Elsevier Ltd. All rights reserved. 收起