摘要 : Objectives: Diffusion imaging represents a new imaging tool for the diagnosis of breast cancer. This study aims to investigate the role of diffusion-weighted MRI with background body signal suppression (DWIBS) for evaluating breas... 展开 Objectives: Diffusion imaging represents a new imaging tool for the diagnosis of breast cancer. This study aims to investigate the role of diffusion-weighted MRI with background body signal suppression (DWIBS) for evaluating breast lesions. Methods: 90 patients were prospectively evaluated by MRI with STIR, TSE-T_2, contrast enhanced THRIVET1 and DWIBS sequences. DWIBS were analyzed searching for the presence of breast lesions and calculating the ADC value. ADC values of ≤1.44 × 10~(-3) mm~2/s were considered suspicious for malignancy. This analysis was then compared with the histological findings. Sensitivity, specificity, diagnostic accuracy (DA), positive predictive value (PPV) and negative (NPV) were calculated. Results: In 53/90 (59%) patients, DWIBS indicated the presence of breast lesions, 16 (30%) with ADC values of > 1.44 and 37 (70%) with ADC ≤ 1.44. The comparison with histology showed 25 malignant and 28 benign lesions. DWIBS sequences obtained sensitivity, specificity, DA, PPV and NPV values of 100, 82, 87, 68 and 100%, respectively. Conclusion: DWIBS can be proposed in theMRI breast protocol representing an accurate diagnostic complement. 收起