摘要 : Background To identify dampness or mold (D/M) in buildings, investigators generally inspect for observable D/M indicators, the presence of which justifies remediation. Investigators may also use microbiological measurement and int... 展开 Background To identify dampness or mold (D/M) in buildings, investigators generally inspect for observable D/M indicators, the presence of which justifies remediation. Investigators may also use microbiological measurement and interpretation strategies with uncertain scientific support. Objective We assessed available evidence supporting uses of spore counts, the microbiological measurement most commonly used to assess D/M. Methods We reviewed published studies assessing relationships between spore counts and observable D/M, across buildings with different observable D/M levels. Results Penicillium/Aspergillus counts were consistently elevated in damp vs. reference (dry or outdoor) locations. Total spore counts provided a weaker, less consistent signal. The most detailed published analysis could distinguish groups of damp homes but not individual damp homes. Significance Evidence did not validate current interpretations of spore count data for identifying single damp homes. Thus, such interpretations rest primarily on professional judgment. An additional series of informative but ineligible articles demonstrated an unconventional, more powerful "statistically based" comparison of multiple indoor vs. outdoor spore counts for identifying elevated indoor spores (and assumed D/M). Findings suggest that validation of enhanced spore trap approaches, including more samples indoors and outdoors plus statistically based comparisons of specific fungal groups, may allow evidence-based microbial identification of probable dampness in individual buildings. 收起