摘要 : Alcohol-related liver disease (ArLD) is a major cause of morbidity and mortality. Effective management requires multi-disciplinary input at every stage of the disease trajectory. We present a typical case to illustrate current evi... 展开 Alcohol-related liver disease (ArLD) is a major cause of morbidity and mortality. Effective management requires multi-disciplinary input at every stage of the disease trajectory. We present a typical case to illustrate current evidence-based investigation and management of a patient with ArLD. This case-based review aims to concisely support the day-to-day decision making of clinicians looking after patients with ArLD, from risk stratification and fibrosis assessment in the community through to managing decompensated disease, escalation care to critical care and assessment for liver transplantation. We summarise the evolving evidence for the benefit of liver transplantation in alcoholic hepatitis, and ongoing controversies shaping future research in this area. ArLD is fundamentally a public health problem, and further efforts are required to implement effective policies to reduce consumption and prevent disease. 收起