摘要 : For many decades, cell-free nucleic acids have been known to be present in peripheral blood. Several studies have identified tumor-specific and/or tumor-associated alterations in the circulating nucleic acids of patients with vari... 展开 For many decades, cell-free nucleic acids have been known to be present in peripheral blood. Several studies have identified tumor-specific and/or tumor-associated alterations in the circulating nucleic acids of patients with various cancers. In recent years, cell-free microRNA (miRNA) have been stably detected in the plasma and serum, like other molecules; their presence in the blood has attracted the attention of researchers due to their potential use as valuable blood biomarkers. 收起