摘要
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Daily food intake plays an important role in the pathogenesis of arthritis. However, an association between arthritis, food intake, and cardiovascular disease (CVD) risk remains unclear. We hypothesized that higher intakes of nutr...
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Daily food intake plays an important role in the pathogenesis of arthritis. However, an association between arthritis, food intake, and cardiovascular disease (CVD) risk remains unclear. We hypothesized that higher intakes of nutrients, fruits, and vegetables are associated with a lower risk of arthritis, osteoarthritis (OA), and rheumatoid arthritis (RA) in the Korean population with various comorbidities. This study aims to identify the association between arthritis, OA, RA, food intake, and CVD risk among the elderly population. We conducted a cross-sectional study of 33,966 eligible subjects aged > 50 years who completed the 2009- 2019 Korea National Health and Nutrition Examination Survey. Logistic regression was used to identify associations between the presence of arthritis, OA, and RA and risk factors and to predict risks of arthritis, OA, and RA based on marginal effects. The prevalence of arthritis (odds ratio [OR] 1.26; 95% confidence interval [CI], 1.15-1.37) and OA (OR 1.24; 95% CI, 1.14-1.36) were significantly higher among individuals with a high risk of CVDs compared with those with low risk. A 2-fold increase in daily vitamin B1, B2, polyunsaturated fatty acids, and n-3 fatty acid consumption is associated with a significantly lower risk of arthritis and OA development. The ORs for high consumption of fruit were 0.72 (0.54-0.95) in arthritis, and 0.70 (0.52-0.94) in OA, in comparison with the low-consumption group. Furthermore, the OR for high consumption of green vegetables was 0.74 (0.55-0.98) in arthritis. Of note, people who have arthritis, or OA, have a significantly increased CVD risk. In conclusion, high consumption of nutrients, fruits, and vegetables was found to be associated with the pres-ence of arthritis and OA. More research is needed to explore whether interactions between intake of nutrients, fruits, and vegetables affect the presence of arthritis, OA, and CVDs. (c) 2021 Elsevier Inc. All rights reserved.
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