摘要 : The depletion of DA in the mPFC did not modif both the basal leve and the VTA- stimulated DA efflux in the Nac, but significantly facili- tated the AMP(20μmol.L~-1)-evoked DA efflux within the NAc. In indicates that the mPFC DA ef... 展开 The depletion of DA in the mPFC did not modif both the basal leve and the VTA- stimulated DA efflux in the Nac, but significantly facili- tated the AMP(20μmol.L~-1)-evoked DA efflux within the NAc. In indicates that the mPFC DA efflux system is in- volved in the regulation of evoked DA release in the NAc. Besides, the AMP-evoked increase of the extra- Ed by SPD(10, 30 mmol.L~-1)microinjection into the mPFC, though this injection of SPD could not alter the response on DA release by the stimulation of the VTA. SPD is capable of enhancing the function of D_1 Receptors in the mPFC, by which if facilitates the inhibi- Tion of DA release in the NAc. 收起