摘要 :
The zona pellucidae is the first important position in sperm/oocyte interactions.Sperm binding to the zona pellucidae is an initial and critical step in fertilization,which is relevant to both of sperm motility and oocyte maturati...
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The zona pellucidae is the first important position in sperm/oocyte interactions.Sperm binding to the zona pellucidae is an initial and critical step in fertilization,which is relevant to both of sperm motility and oocyte maturational stage. However,until recently there was no ideal model to predict fertilization potential of spermand to reveal the mechanism of sperm/oocyte interactions. The hemizona assay (HZA)was first established in human in vitro fertilization(IVF) by using the two matchingzona hemispheres with functional equality which provides many obvious advanages incomparative research of sperm/oocyte binding and interaction. In human IVF, the re-sults have certainly verified the feasibility of the HZA as a test to predict
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摘要 :
It is not clear how oocyte maturation, embryo development and differentiation are regulated, though they are critical to the mechanism of reproduction, in vitro fertilization has been greatly successful in domestic animals and hum...
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It is not clear how oocyte maturation, embryo development and differentiation are regulated, though they are critical to the mechanism of reproduction, in vitro fertilization has been greatly successful in domestic animals and human since the ability of immature mammalian oocytes of undergoing maturation in vitro was first demonstrated by Pincus and Enzmann. Although human in vitro fertilization has experienced immense popularity and more than 5000 test-tube babies have been born to date, serious legal and
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