摘要 : Two series of new thiazolidin-4-one derivatives 4a-c and 8a-e were designed and prepared. All the synthesized compounds were evaluated for their in vitro COX-2 selectivity and anti-inflammatory activity in vivo. Compounds 8c and 8... 展开
作者 | Abdellatif~ Khaled R. A. Abdelgawad~ Mohamed A. Elshemy~ Heba A. H. Alsayed~ Shahinda S. R. |
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作者单位 | |
期刊名称 | 《Bioorganic chemistry》 |
总页数 | 12 |
语种/中图分类号 | 英语 / Q5 |
关键词 | Thiazolidinone Cyclooxygenase inhibition Anti-inflammatory Molecular modeling |
馆藏号 | N2007EPST0000125 |