摘要 : A new alkylation method of acetals has been developed by the reaction of the cationic intermediates, obtained by TESOTf-2,4,6-collidine treatment of acetals, followed by a Gilman reagent. The feature of the method is high chemosel... 展开 A new alkylation method of acetals has been developed by the reaction of the cationic intermediates, obtained by TESOTf-2,4,6-collidine treatment of acetals, followed by a Gilman reagent. The feature of the method is high chemoselectivity, which could not be attained by previously reported methods. Reaction proceeds under weakly basic conditions that acid-labile functional groups can tolerate. 收起