摘要 : A novel synthetic method for methyl 5-substituted thiazole-4-carboxylates (5) by the reaction of methyl 3-substituted 3-bromo-2-isocyanoacrylates(BICA)(1) with hydrogen sulfide in the presence of triethylamine in N,N-dimethylforma... 展开 A novel synthetic method for methyl 5-substituted thiazole-4-carboxylates (5) by the reaction of methyl 3-substituted 3-bromo-2-isocyanoacrylates(BICA)(1) with hydrogen sulfide in the presence of triethylamine in N,N-dimethylformamide was explored, and the reaction mechanism was elucidated. [References: 15] 收起