摘要 : Chemical syntheses of complex-type glycans derived from the eggs of parasitic helminths, Schistosoma mansoni and Schistosoma japonicum were achieved. In addition, their analogs, which lack xylose and/or fucose residue(s), are desc... 展开 Chemical syntheses of complex-type glycans derived from the eggs of parasitic helminths, Schistosoma mansoni and Schistosoma japonicum were achieved. In addition, their analogs, which lack xylose and/or fucose residue(s), are described. These branched sugar chains were synthesized regio- and stereo selectively by using beta-mannosylation, desilylation under high-pressure and glycosylation in frozen solvent as key transformations. (c) 2007 Elsevier Ltd. All rights reserved. 收起