摘要 : An efficient, highly stereoselective synthesis of the C10-C26 portion of pinnatoxin A has been achieved, wherein the key step is a highly stereoselective construction of the 6,5,6-dispiroketal (BCD ring) system by an intramolecula... 展开 An efficient, highly stereoselective synthesis of the C10-C26 portion of pinnatoxin A has been achieved, wherein the key step is a highly stereoselective construction of the 6,5,6-dispiroketal (BCD ring) system by an intramolecular hetero-Michael addition of a hemiketal alkoxide reversibly formed under the influence of lithium methoxide. (C) 2002 Elsevier Science Ltd. All rights reserved. [References: 65] 收起