摘要 : [GRAPHICS] Palladium-catalyzed heterocyclization-coupling sequences have been developed starting from buta- 1,2,3-trienyl carbinols and electron-deficient alkenes. Polysubstituted furans are formed where the heterocyclic ring orig... 展开 [GRAPHICS] Palladium-catalyzed heterocyclization-coupling sequences have been developed starting from buta- 1,2,3-trienyl carbinols and electron-deficient alkenes. Polysubstituted furans are formed where the heterocyclic ring originates from the elements of the butatrienyl carbinol while the electrondeficient olefin is incorporated as a C-3 substituent. In most cases, the reaction proceeds via a Heck-type pathway leading to the efficient formation of 3-vinylfurans. However, couplings with methyl vinyl ketone display a divergent behavior to afford selectively either Heck- or hydroarylation-type products depending on reaction conditions. 收起