摘要 : A series of 3-spirocyclopropanedihydro- and -tetrahydropyrid-4-ones have been synthesized by nitrone cycloaddition to 1,1'-bicyclopropylidene (BCP), chemoselective reduction of the N-O bond of the isoxazolidine ring, and Pd-II-cat... 展开 A series of 3-spirocyclopropanedihydro- and -tetrahydropyrid-4-ones have been synthesized by nitrone cycloaddition to 1,1'-bicyclopropylidene (BCP), chemoselective reduction of the N-O bond of the isoxazolidine ring, and Pd-II-catalyzed cascade rearrangement of the beta-anunocyclopropanol derivatives into the final products. The new tetrahydropyridone derivatives were also prepared by thermal rearrangement of the isoxazolidines. 收起