摘要: The goal of this research is to develop stereoscopic techniques for mammographic imaging and to investigate the feasibility of using stereomammography to improve the sensitivity of mammography for breast cancer diagnosis. During t... 展开 The goal of this research is to develop stereoscopic techniques for mammographic imaging and to investigate the feasibility of using stereomammography to improve the sensitivity of mammography for breast cancer diagnosis. During the project years we have performed extensive investigation of the effects of image acquisition techniques including stereo shift, exposure, and geometric magnification on the depth discrimination capability of digital stereomammography. Software tools have been developed for two high-resolution stereo display workstations The software allows manipulation of the displayed images and provides 3D virtual cursors for the measurement of the depth of a lesion in the image. Observer experiments have been performed to evaluate the stereomammography imaging technique using stereo images of a specially designed 3D modular phantom. A database of stereo images of biopsied breast tissue specimens was collected and observer performance experiments were conducted to compare the accuracy of lesion characterization and margin clearance identification on stereoscopic and monoscopic images. A pilot study was performed to compare radiologists' impressions of full field digital stereomammograms with conventional mammograms obtained from informed consent breast cancer patients. The results of this project indicate that stereomammography is technologically feasible and it is a promising technique that will provide additional 3D information for the detection and characterization of breast lesions. Further studies are therefore warranted to investigate whether stereomammography can improve the sensitivity of mammography for breast cancer detection, especially in dense breasts. 收起