摘要: This research involved the use of proton-induced X-ray emission (PIXE) for occupational health studies of workers exposed to lead and various other toxic elements. Workplace monitoring was conducted by collection and analysis of a... 展开 This research involved the use of proton-induced X-ray emission (PIXE) for occupational health studies of workers exposed to lead and various other toxic elements. Workplace monitoring was conducted by collection and analysis of air filter samples using a cascade impactor to separate the aerosols according to particle size. Biological monitoring was conducted by collection and analysis of blood and urine. The biological measurements were supplemented by the use of AAS and also by various biochemical tests. Preliminary work was also done to set up an in vivo X-ray fluorescence method for determining lead in the finger bone of exposed workers. The most important outcome of this work was to demonstrate that aerosol concentrations of lead in a lead battery factory were significantly elevated over normal background levels (even as compared with a welding factory). Although mostly lower than the maximum permissible concentrations for occupationally exposed people, this kind of exposure was apparently sufficient to cause significant changes in various biochemical parameters, and thus might be a cause for concern. Low correlations between blood-lead and aerosol-lead indicate that workplace monitoring is not always a reliable guide to individual exposure, and that it should therefore be supplemented by biological monitoring of high risk groups. (Atomindex citation 17:001604) 收起