摘要 : Objective To determine the DNA damaging potential and the genotoxicity of individual compounds in pesticide contaminated soil. Methods In the present study, DNA damaging potential of pesticide-contaminated soil and the genotoxicit... 展开 Objective To determine the DNA damaging potential and the genotoxicity of individual compounds in pesticide contaminated soil. Methods In the present study, DNA damaging potential of pesticide-contaminated soil and the genotoxicity of individual compounds present in the soil were assessed using fluorimetric analysis of DNA unwinding assay. Results The contaminated soil sample showed 79% (P＜0.001) of DNA strand break, whereas technical grade of major carbaryl and α-naphthol constituents of the contaminated soil showed 64% (P＜0.01) and 60% (P＜0.02) damage respectively. Conclusion Our results indicate that the toxicity caused by contaminated soil is mainly due to carbaryl and α -napthol, which are the major constituents of the soil sample analyzed by GC-MS. 收起